Research

The
research activities of NanoToxGen group are focused on the field of Health Sciences,
and specifically on the research area of Toxicology. 

Research line 1: Nanotoxicology

One
of the main research lines of the group focuses on the study of the interaction
between nanomaterials and biological systems, the evaluation of the
biocompatibility of these compounds and the factors that influence it, and the
characterization of the possible toxicological effects of nanomaterials in
different in vitro and in vivo systems. This line also includes the development
and validation of new specific tools for biomonitoring studies and nanotoxicity
assessment.

Research line 2: Testing of
compounds with potential biomedical applications

Another
of the group´s research lines consists of the synthesis, characterization and
testing of compounds with potential biomedical applications. In particular,
this line focuses mainly on the synthesis and physicochemical characterization
of new vanadium and molybdenum complexes. Their catalytic activity and the
analysis of their biological activity are also addressed to evaluate their
potential as enzyme mimetic compounds and antitumor agents.

Research line 3: Identification
and validation of biomarkers for risk assessment

Finally,
the group´s third line of research involves the use of biomarkers, model
organisms and cell systems to assess the effects of environmental and
occupational exposure to known or emerging pollutants on health and the
environment. This line also includes the development of new cellular and
molecular biomarkers for the early identification of different pathologies or
medical conditions, focusing in particular on frailty syndrome in the older
adults.